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The content on OpenPep — including peptide profiles, clinical trial summaries, dosing information, and reconstitution calculators — must not be used for:
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Thymosin Beta-4 (Full Length)
For educational and research purposes only. Not medical advice.
Thymosin Beta-4 is the full-length parent of TB-500, present in all cells. Studied for cardiac repair (post-MI), dry eye (RGN-259), and wound healing. More clinical data than TB-500. RegeneRx has ophthalmic and dermal formulations in development.
Best Time
Evening
Method
subcutaneous
Frequency
3x per week
Half-life
~2 hours
Cycle Length
8-12 weeks
Storage
Refrigerate at 2-8°C.
Published Dosing Ranges
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Contraindications
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TB-500 IS a fragment of Thymosin Beta-4 (amino acids 17-23). Combining is redundant — TB-500 mimics the active site of the full-length protein. Choose one, not both.
Journal of the American Heart Association 6 (6) · 2017-06-13
Nature communications 12 (1) :1771 · 2021-03-19
2016-11-01
Psychiatry research 299 :113850 · 2021-05-01
Journal of the American Society for Mass Spectrometry 36 (10) :2079-2093 · 2025-10-01
Mechanism of Action
The full-length parent compound of TB-500. Sequesters G-actin, promotes cell migration, reduces inflammation, stimulates angiogenesis, and has cardiac repair properties.
Reported by the community. These may not be supported by clinical evidence and are not medical recommendations.