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Humanin (Mitochondria-Derived Peptide)
For educational and research purposes only. Not medical advice.
Humanin is a naturally occurring mitochondrial peptide that declines with age. Extensive preclinical data shows cytoprotection across brain, heart, and metabolic systems. Observational studies link higher humanin levels to longevity. Promising but limited clinical data.
Best Time
Morning
Method
subcutaneous
Frequency
Daily
Half-life
~1-2 hours (analogs last longer)
Cycle Length
8-12 weeks
Storage
Refrigerate at 2-8°C.
Published Dosing Ranges
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Contraindications
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Acta neuropathologica 142 (5) :887-898 · 2021-11-01
The journals of gerontology. Series A, Biological sciences and medical sciences 74 (5) :600-607 · 2019-04-23
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 34 (12) :1064-1067 · 2018-12-01
Biology 12 (4) · 2023-04-06
Cell research 14 (6) :507-12 · 2004-12-01
Mechanism of Action
Mitochondria-derived peptide that protects cells from apoptosis, reduces oxidative stress, improves insulin sensitivity, and has cytoprotective effects across multiple organ systems.
Reported by the community. These may not be supported by clinical evidence and are not medical recommendations.