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Mechano Growth Factor (IGF-1Ec Splice Variant)
For educational and research purposes only. Not medical advice.
MGF activates muscle satellite cells for targeted repair and growth. Extremely short half-life requires local injection or PEGylation. Preclinical data shows satellite cell activation but practical use is limited by pharmacokinetics.
Best Time
Immediately post-workout
Method
intramuscular
Frequency
Post-workout
Half-life
~5-7 minutes (must be PEGylated for systemic use)
Cycle Length
4-6 weeks
Storage
Refrigerate at 2-8°C.
Published Dosing Ranges
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Contraindications
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2018-07-16
Frontiers in medicine 12 :1641719 · 2025-01-01
American journal of kidney diseases : the official journal of the National Kidney Foundation 85 (3) :339-352 · 2025-03-01
Molecular phylogenetics and evolution 183 :107779 · 2023-06-01
Science (New York, N.Y.) 377 (6603) :302-306 · 2022-07-15
Mechanism of Action
Splice variant of IGF-1 produced in response to mechanical stress on muscles. Activates muscle satellite cells (stem cells) to initiate repair and growth at the site of damage.
Reported by the community. These may not be supported by clinical evidence and are not medical recommendations.