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Growth Hormone Releasing Peptide-6
For educational and research purposes only. Not medical advice.
GHRP-6 is a potent but less selective GH secretagogue. Known for strong hunger stimulation, it's preferred by those wanting to increase caloric intake for muscle gain. Less popular than Ipamorelin due to cortisol/prolactin side effects.
Best Time
Fasted state — morning and before bed
Method
subcutaneous
Frequency
2-3x daily
Half-life
~15-60 minutes
Cycle Length
8-12 weeks
Storage
Refrigerate at 2-8°C.
Published Dosing Ranges
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Contraindications
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GHRH + GHRP synergy produces amplified GH pulse. GHRP-6 variant adds appetite stimulation, useful for those seeking caloric surplus for muscle gain.
documentedGHRP-6 + Sermorelin follows the classic GHRP+GHRH paradigm. GHRP-6 strongly stimulates appetite via ghrelin mimicry, making this ideal for muscle-gain protocols.
documentedThe Journal of clinical endocrinology and metabolism 95 (5) :2266-70 · 2010-05-01
Clinical endocrinology 64 (6) :667-71 · 2006-06-01
Clinical endocrinology 57 (3) :377-84 · 2002-09-01
Clinical endocrinology 59 (2) :251-7 · 2003-08-01
European journal of endocrinology 141 (2) :180-9 · 1999-08-01
Mechanism of Action
Ghrelin receptor agonist that stimulates GH release from the pituitary. Also significantly increases appetite through ghrelin-mediated hunger signaling, and elevates cortisol and prolactin.
Reported by the community. These may not be supported by clinical evidence and are not medical recommendations.